Carlos Mesquita - Associação Lusitana de Trauma e...
Transcript of Carlos Mesquita - Associação Lusitana de Trauma e...
Hypothermia in trauma
Carlos Mesquita
EUROTRAUMA 2009 ANTALYA
Lusitanian Association of Trauma and Emergency Surgery
Coimbra University Hospital - Portugal
Thermoregulation - physiology
• Normal core body temperature ~ 37 C / 99 F
(from the 1911 Encyclopædia Britannica Eleventh Edition)
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Thermoregulation - physiology
• Constant body temperature mantained by
– Basal metabolic rate
– Muscle activity
– Cutaneous vasoconstriction
– Inhibition of perspiration
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• Mecanisms of heat loss:
Thermoregulation - physiology
– Conduction
• transfer of heat by physical contact with another object or body
– Convection • transfer of heat via a medium such
as air or water
– Radiation • transfer of heat without any medium
through electromagnetic waves
– Evaporation • absorption of heat by a liquid which
then becomes a gas (perspiration, intra-operative loss /
thoracotomy and laparotomy) CM – EUROTRUMA 2009 ANTALYA
• Primary
– Normal thermoregulation + exposure to extreme environment
• Secondary
– Loss of thermoregulatory mechanisms + mild thermal stress
– Intoxication
– Stroke
– Hypothyroid states
– Severe trauma
Accidental hypothermia
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• Depletion of high-energy phosphates (ATP)
+ utilization under anaerobic conditions
= Insufficient heat production organ failure
• Clinical Findings
– Decrease in CNS activity
– Decrease of cardiorespiratory activity • gray, cyanotic • initially cardiovascular stimulation by cathecolamine • later cardiovascular depression
– Increased diuresis (“cold diuresis”)
– Coagulopathy • decrease in platelet function and clotting factor activity
Hypothermia
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• Drop in core temperature to < 35 C / 095 F – rapid or slow
– severity:
• Mild < 35 C / 095 F • Moderate < 32 C / 090 F • Severe < 30 C / 086 F
• Increased risk of VF at < 28 C / 082 F • Asystole commonly occurs at < 22 C / 072 F
low-range thermometer required preferably esophageal
Hypothermia in the absence of traumatic injury
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• Increased mortality with severity of hypothermia
• Any core temperature < 36 C / 097 F
• If < 32 C / 090 F
LIMIT SITUATION = LETHAL TRIAD
Hypothermia in trauma
HYpotHermia AcidosIS CoagulopatHY will feed off each other and start a steep downward spiral, toward death, that is difficult to stop
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• 1/10 major trauma patients experience it – elderly and children at greater risk – decreased heat production in shock – undressing the patient in ressuscitation room – thermoregulation shut off by general anaesthesia – infusion of cold fluids – prolongued exposure of body cavities
• 3/10 death trauma patients hypothermic on arrival
Hypothermia in trauma
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ATLS Key Questions
• Cold injury:
– How does cold affect my patient?
– How do I recognize a cold injury?
– How do I treat local cold injuries?
– How do I treat a systemic cold injury?
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ATLS Key Questions
• How does cold affect my patient?
– Factors
• Temperature / environmental conditions
• Duration of exposure
• Amount of protective clothing
• Patient general state and health
• Immobilization / Moisture
• Vascular disease
• Open wounds
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ATLS Key Questions
• How do I treat a systemic cold injury?
– ABCDE / monitor and support vital functions
– Measure core temperature
– Rewarm
– Assess for associated disorders
– Do not delay transfer
– Not dead until warm and dead
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Rewarming
• Passive external:
– prevention of further heat loss
• remove from the cold environment
– cover with blankets
– allow endogenous heat production to restore normothermia
• not very effective means of restoring and then maintaining normal body temperature
• can result in a shift to anaerobic metabolism and lactic acidosis
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Rewarming
• Active external rewarming
– fluid-circulating heating blankets
– convective air warmers
– reflective blankets
– radiant heat shields
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Rewarming
• Active internal / core rewarming:
– warm intravenous fluids
– airway rewarming
– body cavity lavage
– extracorporeal circulatory techniques
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What’s coming next?
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Round-Trip Journeys to the Afterworld… “… strategies to maintain cerebral and cardiac viability
long enough to gain control of hemorrhage and restore intravascular volume could be life-saving … an entirely new approach to the problem, with emphasis on
– rapid total body preservation, – repair of injuries during metabolic arrest, – and controlled resuscitation,
so-called emergency preservation and resuscitation.”
Shuja F, Almeida JP, Alam HB. Role of hypothermia in hemorrhagic shock. J Organ Dysfunction, 2008;4;3
What’s coming next?
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What’s coming next?
CM – EUROTRUMA 2009 ANTALYA