Hydrocodone/paracetamol/morphine
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Reactions 1441 - 2 Mar 2013 S Hydrocodone/paracetamol/morphine Narcotic bowel syndrome: case report A 24-year-old woman developed narcotic bowel syndrome during treatment with hydrocodone/paracetamol [acetaminophen] and morphine [routes and dosages not stated]. The woman presented to an emergency department with abdominal pain which she had experienced for over a year. The pain was crampy and right-sided. She also had nausea and non-bloody diarrhoea that she had experienced for > 1 year. She had been taking morphine for chronic abdominal pain. Two weeks prior to presentation, she had started treatment with hydrocodone/paracetamol to treat her pain, whilst awaiting a refill of morphine which she had run out of. On examination, abdominal palpation showed diffuse tenderness on her right side. Laboratory tests revealed a serum bicarbonate level of 20 mmol/L. She was treated with saline and her symptoms improved. She was discharged receiving ondansetron. She underwent further evaluation at a gastroenterology service and was diagnosed with narcotic bowel syndrome. The woman was recommended to reduce her dose of narcotic medications. She was weaned off them successfully and her symptoms completely resolved. Author comment: "Based on the patient’s chronic abdominal pain, narcotic usage, and worsening pain despite continual treatment with opiates, the patient was diagnosed with narcotic bowel syndrome." Grover CA, et al. Narcotic bowel syndrome. Journal of Emergency Medicine 43: 992-995, No. 6, Dec 2012. Available from: URL: http://dx.doi.org/10.1016/ j.jemermed.2011.05.025 - USA 803083831 1 Reactions 2 Mar 2013 No. 1441 0114-9954/10/1441-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Transcript of Hydrocodone/paracetamol/morphine
Reactions 1441 - 2 Mar 2013
SHydrocodone/paracetamol/morphine
Narcotic bowel syndrome: case reportA 24-year-old woman developed narcotic bowel syndrome
during treatment with hydrocodone/paracetamol[acetaminophen] and morphine [routes and dosages notstated].
The woman presented to an emergency department withabdominal pain which she had experienced for over a year.The pain was crampy and right-sided. She also had nausea andnon-bloody diarrhoea that she had experienced for > 1 year.She had been taking morphine for chronic abdominal pain.Two weeks prior to presentation, she had started treatmentwith hydrocodone/paracetamol to treat her pain, whilstawaiting a refill of morphine which she had run out of. Onexamination, abdominal palpation showed diffuse tendernesson her right side. Laboratory tests revealed a serumbicarbonate level of 20 mmol/L. She was treated with salineand her symptoms improved. She was discharged receivingondansetron. She underwent further evaluation at agastroenterology service and was diagnosed with narcoticbowel syndrome.
The woman was recommended to reduce her dose ofnarcotic medications. She was weaned off them successfullyand her symptoms completely resolved.
Author comment: "Based on the patient’s chronicabdominal pain, narcotic usage, and worsening pain despitecontinual treatment with opiates, the patient was diagnosedwith narcotic bowel syndrome."Grover CA, et al. Narcotic bowel syndrome. Journal of Emergency Medicine 43:992-995, No. 6, Dec 2012. Available from: URL: http://dx.doi.org/10.1016/j.jemermed.2011.05.025 - USA 803083831
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Reactions 2 Mar 2013 No. 14410114-9954/10/1441-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
