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Vasconcellos, Jaíra Ferreira de

Análise da expressão do oncogene PML-RARααααpor PCR quantitativa em pacientes com leucemia aguda promielocítica / Jaíra Ferreira de Vasconcellos. – Recife : O Autor, 2006.

96 folhas. : il., fig., tab., gráf.

Dissertação (mestrado) – Universidade Federal de Pernambuco. CCB. Genética, 2006.

Inclui bibliografia e anexos. 1. Genética – Biologia molecular. 2. Leucemia

aguda promielocítica – PML-RARαααα . 3. Método da Reação em Cadeia da Polimerase Quantitativa (Q-PCR) – Sistema de Marcação Fluorescente Taqman. I. Título.

577.21 CDU (2.ed.) UFPE 572.865 CDD (22.ed.) BC2006-087

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N-cor HDAC

HDAC N-cor

RXR RXR RARA RARA

RARE RARE

Co-A

Co-ativadores

Doses Fisiológicas de ATRA (10-9 M)

Complexo repressor

A

Complexo repressor

B

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