CURRICULUM VITAE

March, 2017

Paulo de Castro Aguiar

i3S – Instituto de Investigação e Inovação em Saúde http://www.i3s.up.pt INEB – Instituto de Engenharia Biomédica http://www.ineb.up.pt/ Universidade do Porto Rua do Campo Alegre, 823; 4150-180 Porto, Portugal Phone: +351 226 074 900 Email address: pauloaguiar@ineb.up.pt Personal Webpage: http://www.fc.up.pt/pessoas/pauloaguiar

Education

Ph.D. Computational Neuroscience 2001-2006 Institute for Adaptive and Neural Computation, Univ. of Edinburgh, U.K. Supervisor: David Willshaw Co-Supervisor: Mark van Rossum

Thesis title: “A General Hippocampal Computational Model: Episodic and Spatial Memory Combined in a Spiking Model”

M.Sc. Physics (5yrs degree in Portugal, M.Sc.+B.Sc.) 1995-2000

B.Sc. Instituto Superior Técnico, University of Lisbon, Portugal

Final Grade: 80/100

Doctoral Training Program in Biophysics and Biomedical Engineering 2000-2001

Institute of Biophysics and Biomedical Engineering

Faculty of Sciences of University of Lisbon, Portugal

Supervisor: Eduardo Ducla-Soares

Final Grade: 95/100

Advanced Course in Computational Neuroscience Aug 2003

IBRO - International Brain Research Organization

Professional Activities

Principal Investigator – Neuroengineering and Computational Neuroscience

i3S – INEB 2016-now

Research Fellow Mathematical/Computational Biology

IBMC.INEB 2013-2015

Affiliate Professor (Professor Afiliado) Biophysics

Faculty of Medicine of University of Porto, Portugal

2014-now

Investigador Ciência (Assistant Researcher) Biomathematics

Center for Mathematics of University of Porto, Portugal

2008-2013

Lecturer (MD and Doctoral Program in Neuroscience)

Faculty of Medicine of University of Porto, Portugal

2008-now

Lecturer (Master is Mathematical Engineering)

Faculty of Sciences, University of Porto, Portugal

2008-2012

Postdoc - Computational Neuroscience Neuroscience Division, Institute of Molecular and Cellular Biology, PT

2006-2008

Teaching Assistant (in M.Sc. courses)

Neural Computation

Learning from Data

Maths Refresher

University of Edinburgh, U.K. 2002-2004

Research Assistant (research scholarship)

Multidisciplinary Center of Astrophysics, U. Lisbon, Portugal

2000-2001

Invited member of the IST Physics Degree Committee (only non-Professor member)

Instituto Superior Técnico (IST), U. Lisbon, Portugal

2000-2001

Director of the Astronomy Group, part of the IST Students Physics Group

Instituto Superior Técnico (IST), U. Lisbon, Portugal

1999-2000

Teaching Assistant (in B.Sc. courses)

Physics II

Computational Physics

Instituto Superior Técnico (IST), U. Lisbon, Portugal

1998-2000

Area of scientific activity

Theoretical/Computational Neuroscience; Neuroinformatics; in silico Neuroscience; Neural Engineering;

Neural Computation; Mathematical and Computational Models in Biology and Medicine;

Research interests

I am extremely interested in understanding information processing and information storage in biological

systems. I am particularly interested in neuroscience problems involving memory (information) storage

and recollection in spiking networks (not limited to synaptic plasticity); neural computations in specific

circuits/areas, including the hippocampus; nociceptive information processing in the spinal cord. I am also

very interested in neural engineering and hybrid systems where external electronic systems are merged

with neural circuits to reveal, re-establish, or enhance, proper function. A key element in my research is

mathematical modeling and computer simulations, combined with electrophysiology experiments.

Publications

Papers in international scientific journals with referees [total IF = 185.5; mean IF = 4.9; median JIF percentile = 88.4%]

[38] Conde-Sousa E, Szücs P, Peng H, Aguiar P, "N3DFix: An algorithm for automatic removal of

swelling artifacts in neuronal reconstructions.", (2017) Neuroinformatics, 15(1):5-12

[37] Shamarova E, Chertovskih R, Ramos AF, Aguiar P, “Backward-stochastic-differential-equation

approach to modeling of gene expression”, (2017) Phys. Rev. E, 95, 032418

[36] Dias C, Lv H, Picos R, Aguiar P, Cardoso S, Freitas PP, Ventura J, “Bipolar resistive switching in

Si/Ag nanostructures.”, (2017) Applied Surface Science, DOI: 10.1016/j.apsusc.2017.01.140

[35] Lopes CD, Gomes CP, Neto E, Sampaio P, Aguiar P, Pêgo AP, “Microfluidic-based platform to mimic

the in vivo peripheral administration of neurotropic nanoparticles”, (2016) Nanomedicine,

11(24):3205-3221

[34] Neto E, Leitão L, Sousa D, Alves CJ, Alencastre IS, Aguiar P, Lamghari M, “Compartmentalized

microfluidic platforms - the unrivaled refresh of in vitro tools for neurobiological research”, (2016)

J Neuroscience, 36(46):11573-11584

[33] Pereira CL, Teixeira GQ, Ribeiro-Machado C, Caldeira J, Costa M, Figueiredo F, Fernandes R, Aguiar

P, Grad S, Barbosa MA, Gonçalves RM, “Mesenchymal Stem/Stromal Cells seeded on cartilaginous

endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling”,

(2016) Scientific Reports, 6,33836

[32] Sousa DM, Conceição F, Silva D, Leitão L, Neto E, Alves CJ, Alencastre IS, Herzog H, Aguiar P,

Lamghari M, “Ablation of Y1 receptor impairs osteoclast bone-resorbing activity”, (2016) Scientific

Reports, 6,33470

[31] Teixeira G, Pereira C, Castro F, Ferreira J, Lázaro M, Aguiar P, Wilke H, Ignatius A, Barbosa M,

Neidlinger-Wilke C, Gonçalves R, “Anti-inflammatory Chitosan/Poly-ɣ-glutamic acid nanoparticles

control inflammation while remodeling extracellular matrix in degenerated intervertebral disc”,

(2016) Acta Biomaterialia, 42:168-179

[30] Gerós A, Horta R, Aguiar P*, "Facegram - Objective quantitative analysis in facial reconstructive

surgery", (2016) J Biomedical Informatics, 61:1-9

[29] Pereira AJ, Aguiar P, Belsley M, Maiato H, "Inducible fluorescent speckle microscopy", (2016)

Journal of Cell Biology, 212 (2), 245-255

[28] Alencastre I, Sousa D, Alves C, Leitão L, Neto E, Aguiar P, Lamghari M, "Delivery of pharmaceutics

to bone: Nanotechnologies, High-throughput processing and in silico mathematical models.",

(2016) European Cells and Materials Journal, 31: 355-381

[27] Dias C, Guerra M, Ventura J*, Aguiar P*, "Memristor-based Willshaw network: capacity and

robustness to noise in the presence of defects", (2015) Applied Physics Letters, 106, 223505

[26] Neto E, Alves CJ, Sousa DM, Alencastre IS, Lourenço AH, Leitão L, Ryu HR, Jeon NL, Fernandes R,

Aguiar P, Almeida RD, Lamghari M, "Sensory neurons and osteoblasts: close partners in a

microfluidic platform", (2014) Integrative Biology (Camb), 6(6), pp 586-595

[25] Barisic M, Aguiar P, Geley S and Maiato H, "Kinetochore motors drive congression of peripheral

polar chromosomes by overcoming random arm-ejection forces", (2014) Nature Cell Biology,

16(12):1249-56

[24] Silva P, Travassos B, Vilar L, Aguiar P, Davids K, Araújo D, Garganta J, "Numerical relations and skill

level constrain co-adaptive behaviors of agents in sports teams", (2014) PLOS ONE, 9 (9)

[23] Sousa M, Szucs P, Lima D and Aguiar P*, "The pronociceptive dorsal reticular nucleus contains

mostly tonic neurons and frequently shows spontaneous activity without ascending input from

the spinal cord", (2014) J Neurophysiology, 111 (7), pp 1507-1518

[22] Afonso O, Matos I, Pereira A, Aguiar P, Lampson A, Maiato H, "Feedback control of chromosome

separation by a midzone Aurora B gradient", (2014) Science, 345 (6194), pp 332-336

[21] Sousa M, Aguiar P*, “Building, simulating and visualizing large spiking neural networks with

NeuralSyns”, (2014) Neurocomputing, 123, pp 372-380

[20] Castro L, Aguiar P*, “A feedforward model for the formation of a grid field where spatial

information is provided solely from place cells”, (2014) Biological Cybernetics, 108 (2), pp. 133-

143

[19] Silva , Duarte R, Sampaio J, Aguiar P, Davids K, Araujo D, Garganta J, "Field dimension and skill

level constrain team tactical behaviours in small-sided and conditioned games in football", (2014)

Journal of Sports Sciences, 32(20), pp 1888-1896

[18] Horta R, Aguiar P, Monteiro D, Silva A, Amarante JM, “A facegram for spatial-temporal analysis of

facial excursion: Applicability in the microsurgical reanimation of long-standing paralysis and

pretransplantation”, (2014) Journal of Cranio-Maxillofacial Surgery, 42(7), 1250–1259

[17] Silva P, Aguiar P, Duarte R, Davids K, Araújo D, Garganta J, "Effects of pitch size and skill level on

tactical behaviours of association football players during small-sided and conditioned games",

(2014) Intl J of Sports Science and Coaching, 9(5), pp 993-1006

[16] Horta R, Aguiar P, Silva P, Monteiro D, Amarante JM, "Facial disfigurement: Restoration of facial

dynamics in a patient with concomitant facial paralysis and blindness", (2014) Journal of

Reconstructive Microsurgery, 30 (3), pp. 207-210

[15] Aguiar P*, Sousa M, Szucs P, “Versatile morphometric analysis and visualization of the three-

dimensional structure of neurons”, (2013) Neuroinformatics, 11 (4), pp. 393-403

[14] Moutinho-Pereira S, Stuurman N, Afonso O, Hornsveld M, Aguiar P, Goshima G, Vale RD, Maiato

H, “Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells”,

(2013) PNAS - Proceedings of the National Academy of Sciences of the United States of America,

110 (49), pp. 19808-19813

[13] Guimarães J, Moura E, Silva E, Aguiar P, Garrett C, Vieira-Coelho MA, “Locus coeruleus is involved

in weight loss in a rat model of Parkinson's disease: An effect reversed by deep brain stimulation”,

(2013) Brain Stimulation, 6 (6), pp. 845-855

[12] Conde-Sousa E, Aguiar P*, “A working memory model for serial order that stores information in

the intrinsic excitability properties of neurons”, (2013) Journal of Computational Neuroscience,

35 (2), pp. 187-199

[11] Horta R, Monteiro D, Silva A, Amarante JM, Aguiar P*, “Evaluation of a facial transplant candidate

with a facegram: A baseline analysis”, (Plastic and Reconstructive Surgery (2013) 132 (479e-480)),

(2013) Plastic and Reconstructive Surgery, 132 (4), pp. 1040-1041

[10] Silva P, Garganta J, Araújo D, Davids K, Aguiar P, “Shared knowledge or shared affordances?

Insights from an ecological dynamics approach to team coordination in sports”, (2013) Sports

Medicine, 43 (9), pp. 765-772

[9] Szucs P, Luz LL, Pinho R, Aguiar P, Antal Z, Tiong SYX, Todd AJ, Safronov BV, “Axon diversity of

lamina I local-circuit neurons in the lumbar spinal cord”, (2013) Journal of Comparative Neurology,

521 (12), pp. 2719-2741

[8] Carneiro J, Duarte-Pereira S, Azevedo L, Castro LFC, Aguiar P, Moreira IS, Amorim A, Silva RM,

“The Evolutionary Portrait of Metazoan NAD Salvage”, (2013) PLoS ONE, 8 (5), art. no. e64674

[7] Pinto S, Krishna R, Dias C, Pimentel G, Oliveira GNP, Teixeira JM, Aguiar P, Titus E, Gracio J, Ventura

J, Araujo JP, “Resistive switching and activity-dependent modifications in Ni-doped graphene

oxide thin films”, (2012) Applied Physics Letters, 101 (6), art. no. 063104

[6] Castro L, Aguiar P*, “Phase precession through acceleration of local theta rhythm: A biophysical

model for the interaction between place cells and local inhibitory neurons”, (2012) Journal of

Computational Neuroscience, 33 (1), pp. 141-150

[5] Pais-Vieira M, Aguiar P, Lima D, Galhardo V, “Inflammatory pain disrupts the orbitofrontal

neuronal activity and risk-assessment performance in a rodent decision-making task”, (2012) Pain,

153 (8), pp. 1625-1635

[4] Aguiar P*, Sousa M, Lima D, “NMDA channels together with L-type calcium currents and calcium-

activated nonspecific cationic currents are sufficient to generate windup in WDR neurons”, (2010)

Journal of Neurophysiology, 104 (2), pp. 1155-1166

[3] Aguiar P*, Mendonça L, Galhardo V, “OpenControl: A free opensource software for video tracking

and automated control of behavioral mazes”, (2007) Journal of Neuroscience Methods, 166 (1),

pp. 66-72

[2] Vourvouhaki E, Carvalho C, Aguiar P, “Model for Osteosarcoma-9 as a potent factor in cell survival

and resistance to apoptosis”, (2007) Physical Review E - Statistical, Nonlinear, and Soft Matter

Physics, 76 (1), art. no. 011926

[1] Aguiar P, Willshaw D, “Hippocampal mossy fibre boutons as dynamical synapses”, (2004)

Neurocomputing, 58-60, pp. 699-703

Papers in national scientific journals with referees [2] Dias C, Guerra L, Aguiar P, Ventura J, “The concept of Metal-Insulator-Metal nanostructures as

Adaptive Neural Networks”, (2015) U.Porto J. of Engineering

[1] Conde-Sousa E, Aguiar P*, "Detailed mathematical models in neurobiology - Storing information

in membrane conductances dynamics", (2012) Bulletin Centro Internacional de Matemática, Jan.

Book Chapters [2] Dias C, Ventura J, Aguiar P, "Memristive-based neuromorphic applications and associative

memories", (2017) in Advances in Memristors, Memristive Devices and Systems, Elsevier, pp 305-

342

[1] Neto E, Paramos-de-Carvalho D, Lourenco A, Aguiar P, Lamghari M, "Compartmentalized

microfluidic platforms as tool of choice to study the interaction between neurons and

osteoblasts", (2015) Neuromethods, 103:161-179

Peer reviewed conferences [23] Monteiro J, Oliveira H, Aguiar P, Cardoso J, “A Depth-Map Approach for Automatic Mice Behavior

Recognition”, IEEE International Conference on Image Processing 2014, pp 2261-2265, doi:

10.1109/ICIP.2014.7025458

[22] Castro L and Aguiar P*, "A model for grid cells where spatially correlated place cells compete for

the grid map nodes", CNS 2013, BMC Neuroscience 2013, 14(Suppl 1):P2; doi:10.1186/1471-2202-

14-S1-P2

[21] Conde-Sousa E and Aguiar P*, "Conversion from spatial patterns of activity to sequences of

neuronal activations using gate interneurons", CNS 2013, BMC Neuroscience 2013, 14(Suppl

1):P3; doi:10.1186/1471-2202-14-S1-P3

[20] Sousa M, Szucs P and Aguiar P*, "Reduction in inhibitory control is sufficient to generate

hyperalgesia in a spiking model of nociceptive integration in the superficial dorsal horn", CNS

2013, BMC Neuroscience 2013, 14(Suppl 1):P1; doi:10.1186/1471-2202-14-S1-P1

[19] Neto E, Aguiar P, Almeida R and Lamghari M, “Quantitative method for assessing axonal

outgrowth on microfluidic devices”, Bioimaging 2012

[18] Conde-Sousa E and Aguiar P*, “A working memory model capable of storing sequences of

patterns without using synaptic plasticity”, Champalimaud Neuroscience Symposium 2012

[17] Castro L and Aguiar P*, “Inhibitory synaptic plasticity, allied with place fields competition and

compactness, can give rise to grid-like firing pattern”, Champalimaud Neurosci. Symposium 2012

[16] Castro L and Aguiar P*, "Phase precession through acceleration of local theta rhythm: a

biophysical model for the interaction between complex spike cells and theta cells", CNS 2011,

BMC Neuroscience 2011, 12(Suppl 1):P2 (18 July 2011) doi:10.1186/1471-2202-12-S1-P2

[15] Aguiar P* and Szucs P, "Detailed visualization and morphometric analysis of reconstructed

neurons using Blender and Python", CNS 2011, BMC Neuroscience 2011, 12(Suppl 1):P323 (18 July

2011) doi:10.1186/1471-2202-12-S1-P323

[14] Luz LL, Pinho R, Aguiar P, Antal Zs, Todd A, Safronov BV and Szucs P, "Morphological analysis of

lamina I local-circuit neurons in the lumbar spinal cord of the rat", Champalimaud Neuroscience

Symposium 2011

[13] Sousa M, Aguiar P and Szucs P, "Towards biophysically realistic models of the neuronal dynamics

in the reticular nucleus of medulla oblongata", Champalimaud Neuroscience Symposium 2011

[12] Conde-Sousa E and Aguiar P*, "Storing information in membrane conductances dynamics -

working memory without synaptic plasticity", Champalimaud Neuroscience Symposium 2011

[11] Aguiar P*, Sousa M and Lima D, "Analysis of the mechanisms underlying windup using a detailed

biophysical model of WDR neurons", CNS 2010, BMC Neuroscience 2010, 11(Suppl 1):O14,

doi:10.1186/1471-2202-11-S1-O14

[10] Aguiar P*, Rodrigues M, "Neuronal connectivity inference from spike trains using an empirical

probabilistic causality measure", CNS 2010, BMC Neuroscience 2009, 10(Suppl 1):P169,

doi:10.1186/1471-2202-10-S1-P169

[9] Sousa M and Aguiar P*, "NetBuilder: a tool for constructing large and complex neural networks",

Portuguese Society for Neurosciences Meeting 2009, doi: 10.3389/conf.neuro.01.2009.11.068

[8] Aguiar P*, "NeuralSyns: A Novel Tool For Simulating Large Neuronal Networks With Complex

Architectures", Portuguese Society for Neurosciences Meeting 2009, doi:

10.3389/conf.neuro.01.2009.11.045

[7] Aguiar P*, "Functional model for nociceptive allodynia and hyperalgesia", COSYNE 2008

[6] Aguiar P* and Willshaw D, "Simulating large and heterogeneous networks of spiking neurons with

SpiNet", CNS 2007, BMC Neuroscience 2007, 8(Suppl 2):P9, doi:10.1186/1471-2202-8-S2-P9

[5] Aguiar P*, "Hippocampal place cells and coding through constellations of active neurons", CNS

2006

[4] Aguiar P* and Willshaw D, "Hippocampal mossy fibres", CNS 2003

[3] Mourão A, Aguiar P, Cruz M and Lopes A, "Nearby Type Ia supernova searches: the Portuguese

experience and plans for the future.", in Astronomy and Astrophysics: Recent developments,

Proceedings of the 10th Portuguese Meeting in Astronomy and Astrophysics 2011, World

Scientific 2001

[2] Cruz MJ, Aguiar P, Lopes AM and Mourão AM, "Type Ia Supernova", in "Simililarities and

universality in relativistic flows", PhD Euroconference 2001, Logos Verlag Berlin, 2001.

[1] Aguiar P, Paulo S, David A and Rosa A, "EEGSolver - Brain Activity and Genetic Algorithms", ACM

- Symposium on Applied Computing Proceedings 2000, Italy 2000;

Other Conferences [7] Sousa M, Antal Z, Conde-Sousa E, Aguiar P and Szucs P, “Distinct Patterns of Synaptic Integration

in the Dendrites of Tonic Spinal Lamina I and Lateral Spinal Nucleus Neurons”, IBRO Workshop

2014. January 16-17. Debrecen, Hungary.

[6] Sousa M, Szucs P and Aguiar P*, "Parameterization of ionic currents dynamics in tonic firing

neurons of the dorsal reticular nucleus (DRt)", FENS 2012

[5] Szucs P, Luz L, Pinho R, Aguiar P, Antal Z, Tiong S, Todd A and Safronov B, "Morphological analysis

of lamina I local-circuit neurons of the lumbar spinal cord", FENS 2012

[4] Sousa M and Aguiar P*, "Building complex neuronal network architectures with NetBuilder", FENS

Abstr., vol.5, 207.7, FENS 2010

[3] Aguiar P*, Sousa M and Galhardo V, "Dependence of windup with substance P release dynamics:

a detailed biophysical model approach", FENS Abstr., vol.4, 124.1, FENS 2008

[2] Aguiar P* and Galhardo V, "Computational model of nociceptive integration in laminae I and II",

FENS Abstr., vol.3, A144.2, FENS 2006

[1] Aguiar P* and Willshaw D. "A General Model for Spatial Memory and Pattern Recognition", FENS

2004

Scientific Software

[only the most important; more at http://www.fc.up.pt/pessoas/pauloaguiar/software.html]

[4] Py3DN: morphometric analysis and visualization of the 3D structure of neurons,

http://sourceforge.net/projects/py3dn/

[3] AxoFluidic: quantification of axonal plexus spatial coverage in microfluidic devices,

http://tinyurl.com/AxoFluidic

[2] NeuralSyns: simulation environment for large and heterogeneous spiking networks,

http://sourceforge.net/projects/neuralsyns/

[1] OpenControl: automation for behavioral neuroscience with video tracking and other tools,

http://sourceforge.net/projects/opencontrol/

Number of registered downloads (@Nov 1st, 2016): OpenControl +10600 downloads (since Apr 2007);

NeuralSyns +400 downloads (since Sep 2009); Py3DN +900 downloads (since Apr 2013); AxoFluidic +60

downloads (since Jan 2014). Total registered downloads = +11,900.

Scientific Reviewer/Referee invitations

Institutions: Foundation for Polish Science; Portuguese Agência Nacional de Inovação (ANI); External

Expert for EU COST Actions.

Journals: Journal of Neurophysiology [SJR: Physiology, rank 5%; IF 3.30]; Neuroinformatics [SJR: Health

Informatics, rank 9%; IF 3.14]; IEEE Transactions on Medical Imaging [SJR: Computer Science

Applications, rank 2%; IF 3.80]; PLoS ONE [SJR: Medicine (miscellaneous), 10%; IF 3.53]; Int. Journal of

Neural Systems [SJR: Computer Networks and Communications, 31%; IF 5.05]

Experience as scientific adviser

[11] Luís Pedro de Araújo Leitão (Phd Student) - "Eavesdropping on the crosstalk between sensory

innervation and bone remodelling: a microfluidic approach", Doctoral Program in Biomedical

Engineering, University of Porto [Set 2015 - ONGOING] - Co-Supervisor

[10] Catarina José Loureiro da Silva Dias (Phd Student) - "Memristor Based Adaptive Neural Networks",

Doctoral Program in Physics, Faculty of Sciences of University of Porto [Set 2013 - ONGOING] - Co-

Supervisor

[9] Mónica Catarina Cerquido (MSc Student) - "Fabrication of biocompatible gold mushroom-shaped

microelectrodes for the recording of neuronal signals", Masters in Physics, Faculty of Sciences of

U. of Porto [Set 2015 – Out 2016] – Co-Supervisor [Final grade 20/20]

[8] João Alexandre da Silva Pereira Reis (MSc Student) - "Simulation and analysis of neuro-memristive

hybrid circuits", Masters in Physics, Faculty of Sciences of U. of Porto [Set 2015 – Out 2016] - Main

Supervisor [Final grade 17/20]

[7] Ana Filipa Gerós (MSc Student) - "Capture and Analysis of the Trajectories of Anatomical Points

on the Face to Support and Evaluate Reconstructive Plastic Surgery", Masters in Bioengineering,

Faculty of Engineering of U. of Porto [Set 2014 – Jul 2015] - Main Supervisor [Final grade 19/20]

[6] Ricardo Horta (PhD Student) - “Facial disfigurement: microsurgical autologous reconstruction of

severe defects and facial transplantation”, Faculty of Medicine - University of Porto [Set 2012 –

Jul 2015] - Co-Supervisor [Concluded with "Distinction" grade]

[5] Maria Mafalda Sousa (Phd Student) - "Construction and analysis of detailed biophysical models

for DRt and Lamina I neurones", Doctoral Program in Neuroscience (PDN), Faculty of Medicine -

University of Porto [Oct 2009 - Nov 2014] - Main Supervisor [Concluded with "Distinction" grade]

[4] Eduardo Conde-Sousa (PhD Student) - "Spiking neural networks and applications in working

memory", Doctoral Program in Applied Mathematics (PDMA), Faculty of Sciences - University of

Porto [Sep 2010 - Oct 2014] - Main Supervisor [Concluded with "Distinction" grade]

[3] Maria Luísa Castro (PhD Student) - "How grid cells contribute to the formation of place fields",

Doctoral Program in Applied Mathematics (PDMA), Faculty of Sciences - University of Porto [Sep

2009 - Jul 2013] - Main Supervisor [Concluded with “Distinction” grade]

[2] Mariana Cunha (MSc Student) - "Quantification of flux and time decay of microtubules in the

mitotic spindle", Master in Mathematical Engineering, Faculty of Sciences - University of Porto

[Sep 2011 - Out 2012] - Main Supervisor [Final grade 19/20]

[1] João Monteiro (MSc Student) - "Behavioural pattern recognition in lab animals", Master in

Biomedical Engineering, Faculty of Engineering - University of Porto [Sep 2011 - Sep 2012] - Co-

Supervisor [Final grade 17/20]

Participation in R&D projects and projects grants/funding

[9] 2016-2018: Team member co-responsible for project formulation and core tasks in "Hybrid

neuron-memristor adaptive platform (NeuronMAP)"; FCT grant: PTDC/CTM-NAN/3146/2014

[8] 2016-2018: Team member responsible for core tasks in "Combinatorial regenerative strategy to

potentiate axon regeneration and improve functional recovery after spinal cord injury"; Santa

Casa da Misericórdia de Lisboa – Prémio Melo e Castro grant

[7] 2016-2018: Team member co-responsible for project formulation and core tasks in " Sensory

innervation in the complex orchestration of bone regeneration: interplay in microfluidics

platforms"; FCT grant: PTDC/BIM-MED/4041/2014

[6] 2016-2018: Team member responsible for core tasks in "Biodegradable dendrimers for targeted

neuroprotective therapies in stroke "; FCT grant: PTDC/CTM-NAN/3547/2014

[5] 2016-2018: Team member responsible for core tasks in "Spatiotemporal control of mitotic

spindle assembly"; FCT grant: PTDC/BEX-BCM/1758/2014

[4] 2011-2015: Team member co-responsible for project formulation and core tasks in "Memristor

Based Adaptive Neural Networks (MemBrAiNN)"; FCT grant: PTDC/CTM-NAN/122868/2010

[3] 2013-2015: Team member responsible for core tasks in "Y1 receptor based therapy for local bone

repair: Antagonist behavior and delivery in challenged bone microenvironment"; FCT Grant:

PTDC/BIM-MED/1047/2012

[2] 2007-2010: PI (coordinator) of "Theoretical models of nociceptive information processing and

transmission in the spinal cord´s dorsal horn"; FCT grant: PTDC/SAU-NEU/68929/2006

[1] 2000-2001: Team member of the supernovae data analysis group - CENTRA: Astrophysics

Multidisciplinary Group at IST; "Study of Type Ia supernovae and their cosmological implications";

FCT grant: PESO/ESO/P/PRO/1257/98

Prizes and awards received

2015 Prémio Melo e Castro (team member) Santa Casa da Misericórdia de Lisboa, Portugal 2015 Pfizer Best Paper Award (co-author) Pfizer Pharmaceuticals

2014 INCF 2014 Research Visit Award International Neuroinformatics Coordinating Facility 2008 FENS 2008 Travel Award SPN (Portuguese Neuroscience Society) 2006 Postdoctoral fellowship FCT, MCTES Portugal 2005 Postdoctoral fellowship IBMC, UP, Portugal 2000 PhD Scholarship FCT, MCTES Portugal

Invited Talks

Seminars in Research Centers, Universities and Research Institutes: 32+ 2002-2017

Invitations for Public Awareness Talks (in Public Libraries, Universities, Schools): 20+ 2007-2017

Organization of Workshops, Conferences and Short-Courses

[10] "Workshop on NeuralEngineering" [tinyurl.com/neuroengineering], 2017

[9] "5th International Symposium in Applied Bioimaging" [www.bioimaging2016.i3s.up.pt/], 2016

[Conference Co-Organizer]

[9] "4th International Symposium in Applied Bioimaging" [http://www.bioimaging2015.ineb.up.pt/],

2015 [Conference Co-Organizer]

[8] "1st Porto Meeting in Mathematics and Biology" [http://cmup.fc.up.pt/cmup/biomath/], 2015

[Co-Organizer]

[7] "3rd International Symposium in Applied Bioimaging" [http://www.bioimaging2014.ineb.up.pt/],

2014 [Co-Organizer]

[6] "Mathematical Neuroscience Workshop" [http://www.fc.up.pt/neuromath/] (1 day workshop),

Univ. of Porto, 2012 [Main Organizer]

[5] "Introduction to Scientific Programming with MATLAB" (6 days course), Center for Mathematics

of Univ. of Porto, 2010, 2011, 2012, 2013, 2015 [Main Organizer]

[4] "Topics in Theoretical Neuroscience and Computational Neuroscience", (1 day workshop)

Institute of Molecular and Cellular Biology (IBMC), 2009, 2010 [Main Organizer]

[3] "Introduction to NEURON simulation environment" (1 day workshop), Institute of Biophysics and

Biomedical Engineering (IBEB), Faculty of Sciences of Univ. of Lisbon, 2008 [Main Organizer]

[2] "Introduction to Theoretical Neuroscience" (5 days Workshop), Institute of Molecular and

Cellular Biology (IBMC), 2007 [Main Organizer]

[1] "Topics in Computational Neuroscience", (4 days course), 2006, 2008, Braga [invited by the

Portuguese Society of Cognitive Sciences]

Academic Degrees jury participation

[4] PhD Thesis defense (Neuroscience): “LocoMouse: a novel system for studying the role of

cerebellum in gait coordination” by Ana Sofia Rodrigues Machado; Fundação Champalimaud -

MIT-Portugal, Portugal, 2016

[3] PhD Thesis defense (Mathematical Neuroscience): “Efficient storage and retrieval of memories

in neural networks” by João Sacramento; Instituto Superior Técnico, Portugal, 2014

[2] PhD Thesis defense (Mathematical Neuroscience): “Multi-bump solutions in dynamic neural

fields: Analysis and Applications” by Flora Ferreira; University of Minho, Portugal, 2014

[1] PhD Thesis defense (Biophysics): “Numerical modelling in Transcranial Magnetic Stimulation” by

Ricardo Salvador; Institute for Biophysics and Biomedical Engineering (IBEB), University of

Lisbon, Portugal, 2009

Human Languages

Language Reading Writing Conversation

Portuguese Very good Very good Very good English Very good Very good Very good French Good Basic Basic Japanese Very Basic Very Basic -

Computer Languages

Language Coding Decoding Debugging

C Very good Very good Very good MATLAB Very good Very good Very good NEURON Very good Very good Very good VBasic Very good Very good Very good C++ Good Good Good Python Good Good Good Mathematica Good Good Good LaTeX Good Good Good Equally at ease with GNU-Linux and Windows * OS.